This book chapter advances SDGs 3 and 17 by discussing available data regarding the effects of genetic variants on the clinical and pathological characteristics of “frontotemporal dementia” (FTD). The term “frontotemporal dementia” (FTD) defines a group of related diseases resulting from progressive degeneration of the temporal and frontal lobes. These areas play a significant role in decision-making, behavioral control, emotion, language, and motor functions.