This Viewpoint supports Sustainable Development Goal 3 by discussing the effects of the FDA's approval of aducanumab, a treatment for early-stage Alzheimer's disease, despite its limited clinical benefit, as well as the decision of the Centers for Medicare and Medicaid Services to restrict coverage to individuals enrolled in clinical trials. The authors note that these decisions have led to a confusing landscape for patients with Alzheimer's disease.

Human immunodeficiency virus and Simian immunodeficiency (SIV) are highly immune evasive viruses with few vulnerabilities. Cytomegalovirus vector-programmed MHC-E-restricted CD8+ T cells can mediate complete replication arrest of primary SIV infection with subsequent viral clearance; this approach may be promising for putative vaccines or immuno-therapeutics against HIV.

The introduction of long-acting injectable pre-exposure prophylaxis adds to the choice of HIV-prevention options; this study assesses the potential impact of roll-out in the refion with the highest HIV burden.

Good paper on how electroencephalography monitoring is being used as a method to diagnose Alzheimer's.

As the primary public health strategy for controlling the 2022 Mpox outbreak, it is critical to evaluate the impact of Mpox vaccination campaigns for transgender people and gay, bisexual and other men who have sex with men (T/GBM). We measured vaccine uptake and associated factors among T/GBM clients of an urban STI clinic in British Columbia (BC)

TB is often reported in people with HIV, in whom isoniazid preventive therapy (IPT) is a treamtent regimen used to prevent TB infection. However, when mothers with HIV recieived IPT during their pregnancy, their babies were associated with an increased risk low birth weight, preterm birth, and becoming under weight. Males seemed to be particularly effected. This brings into question the use of IPT in pregnant women with HIV as the health-care communitry seeks to reach SDGs 3.1, 3.2, and 3.3.

The article describes how to turn waste plastics into high-quality liquid oils by thermal and catalytic pyrolysis.

This Article supports SDG 3 by showing an association between some types of unpaid work (housework and caring for adults) and negative effects on mental health. Other types of unpaid work (childcare for women and outdoor work for men) were associated with positive effects on mental health. The authors note that, although tasks such as housework and care duties are necessary, the disproportionate burden of such tasks on women should be addressed.

This mixed methods study evaluated the experiences and perceptions of adult patients before, during, and after allogeneic HSCT as a cure for SCD. SCD patients generally experience improvement of physical, mental, and social health and are able to pursue life goals after HSCT. However, the new post-transplantation reality also confronts patients with challenges that potentially can influence their HRQOL.

This Personal View supports SDGs 3 and 13 by developing a framework to maximise the influence of the health community on decarbonisation and identifying practical approaches by which to implement this framework.