This content aligns with Goal 3: Good Health by exploring the systemic nature of attention-deficit hyperactivity disorder (ADHD) and its associations with other physical and mental health issues, emphasizing the need for comprehensive treatment approaches that address various underlying factors, including autonomic dysfunction and neuroinflammation. By proposing new targets for treatment, the chapter promotes a more holistic understanding of ADHD that can lead to improved health outcomes for affected individuals. Additionally, it supports Goal 10: Reduced Inequalities by highlighting the importance of recognizing and addressing the complex interplay of conditions that often accompany ADHD, ensuring that all individuals receive equitable and effective care tailored to their unique health needs, regardless of their background or circumstances.