This content links with Goal 3: Good health and well-being and Goal 10: Reduced Inequalities by providing information about 22q11.2DS as a model for understanding rare and frequent congenital anomalies and medical conditions, which could provide the chance to better understand these distinct conditions while affording opportunities for translational strategies across the lifespan for both patients with 22q11.2DS and individuals with these associated features in the general population.