This chapter advances SDG 6, 12, and 13 by examining the emergence of water sustainability aspects in recent virtual water trade (VWT) literature, highlights the recent advances and remaining issues in evaluating the water sustainability of agriculture globally, and makes recommendations for future scientific research and societal change: consider groundwater both at the local scale and at the global scale; improve our understanding of groundwater storage and dynamics with new models and data; and raise the profile of groundwater sustainability in governance frameworks to eventually end environmental damages of groundwater exploitation.