In 2018, Dr. Prajwal Rajbhandari was awarded the first prize of the Elsevier Foundation Green and Sustainable Chemistry Challenge for his project, “Guava leaves as natural preservatives for farmers of Nepal.” Due to a lack of viable non-toxic preservatives, or cold chain technologies, one-third of Nepal’s produce is spoiled before it reaches market each year. Dr. Rajbhandari’s project taps the antioxidant and antimicrobial properties of guava leaves to make a water-based, sprayable natural preservative, contributing to SDGs 2, 12 and 15. Two years later, we interviewed Dr. Rajbhandari about his experience as a winner, as well as the upcoming steps for his project.