Data centres support artificial intelligence (AI) development but place rapidly increasing demands on electricity and freshwater resources, with cooling representing a significant portion of their total energy consumption. Wastewater treatment plants (WWTPs) discharge large volumes of treated effluent with substantial cooling potential; however, their integration with data centre infrastructure has not been evaluated. Here we construct a global geodatabase of over 4775 data centres and 57,547 municipal WWTPs across 98 countries, integrating spatial analysis, engineering systems modelling, optimisation, and life-cycle assessment to quantify the benefits of combining treated water reuse with bidirectional thermal recovery. The analysis reveals a strong global spatial co-occurrence between data centres and WWTPs, enabling optimized national-scale pairings in which treated effluent is used for data centre cooling and the return heat is recovered to support sludge drying and anaerobic digestion. This symbiotic approach reduces greenhouse gas emissions by approximately 84 million tonnes of CO
Elsevier, Environmental Science and Ecotechnology, Volume 31, May 2026