This chapter directly supports SDG 2 (Zero Hunger) by addressing soil salinization, which threatens 22-33% of cultivated farmland globally and could affect 50% of arable land by 2050. The research on salt-tolerant microorganisms and their role in maintaining soil health provides crucial knowledge for developing sustainable agricultural practices that can enhance crop production in saline-affected regions, ultimately contributing to global food security. The chapter also connects to SDG 15 (Life on Land) as it examines how salinity disrupts ecosystem structure, processes, and functions, affecting microbial diversity, soil nutrient cycling, and biodiversity. Understanding soil microbiome dynamics under salt stress is essential for developing strategies to restore degraded soils and maintain terrestrial ecosystem stability.