This review examines bioaerosols (airborne particles from biological sources like plants, animals, fungi, bacteria, and viruses) and their relationship to asthma, highlighting that different bioaerosols affect asthma through various pathways and individual susceptibility varies significantly. The article emphasizes that while exposure to certain bioaerosols like allergens, mold, and pathogenic viruses can trigger asthma symptoms and exacerbations, some early-life exposures to diverse microbial communities may actually provide protective effects against asthma development .