Interventional Psychiatry – Chapter 23: Focused ultrasound for psychiatric indications

Focused ultrasound (FUS) is an incisionless surgical procedure that uses nonionizing energy to precisely ablate tissue for disconnecting circuits or to perform neuromodulation in treatment-resistant psychiatric disorders. Preliminary open-label studies in obsessive-compulsive disorder (OCD) and major depressive disorder (MDD) demonstrate favorable efficacy and safety profiles. This chapter provides an overview of the FUS technique and its applications in psychiatric disorders.