Owing to its versatility, biomass can be used for a range of CO2 mitigation and removal options. The recent adoption of end-of-century temperature targets at the global scale, along with mid-century economy-wide net zero emission targets in Europe, has boosted demand forecasts for this valuable resource. Given the limited nature of sustainable biomass supply, it is important to understand most efficient uses of biomass, both in terms of avoided CO2 emissions (i.e., substituted energy and economic services) and CO2 removal.