In this review, Hu et al. summarize fluid biomarker findings across 12 anti-amyloid-β clinical trials. The emerging biomarker data provide evidence of impact of the new therapies on the underlying pathophysiological processes of the AD, supporting the presence of a disease-modifying effect.
This study demonstrates that the Psychological Telephone Triage System (PTT) is an effective and cost-efficient method for early identification of patients with urgent cognitive impairment, particularly in the context of Alzheimer’s disease (AD), helping to reduce unnecessary on-site visits and healthcare burden. The findings suggest that implementing this interdisciplinary pre-screening and triage process can improve management of the rising demand for dementia assessments, especially with new therapeutic options and increasing prevalence of dementia globally.
This study shows that the Cognitive Stimulation Therapy program can significantly improve general cognition, communication, and reduce depression in people living with dementia, regardless of the underlying pathology. However, the effects vary by dementia subtype, with some gains maintained long-term in vascular dementia (VaD) but not in Alzheimer, especially regarding narrative abilities and depressive symptoms, highlighting the importance of personalized approaches.
Review on the study of active peptides in AD and PD, deals with role of inflamation, synaptic plasticity, and other learning, memory and cognitive functions related to AD
Elsevier,
Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Volume 1, Seventh Edition, 2025, pp 99-113
This content aligns with Goal 3: Good Health and Wellbeing and Goal 9: Industry, Innovation, and Infrastructure by discussing the role of genetic variants found to affect cholinergic and noncholinergic neurotransmission.
This review investigates the connection between Type 2 Diabetes Mellitus and Alzheimer's disease, focusing on common mechanisms and the potential of traditional Indian herbs to manage both conditions. It also addresses the challenges and innovative strategies in delivering herbal formulations.
This study found that female 5XFAD mice exhibit early impairments in prefrontal-dependent cognitive functions and increased activity of prefrontal PV neurons, unlike their male counterparts. These findings suggest a potential mechanism for the higher risk of Alzheimer's disease in women, highlighting sex-specific early deregulation in the prefrontal cortex.
This perspective provides recommendations and strategies for the urban ecosystem rehabilitation of future cities, placing biodiversity and ecosystem services at the core of designing healthy and sustainable urban spaces.
Globalization, westernization, and urbanization over the last decades, leading to changes in dietary habits as well as food production, consequently, rising non-communicable diseases (NCDs) and environmental degradation. This study attempts to identify Thailand's dietary changes, considering health and sustainability aspects, and to determine correlations between these changes and NCD cases as well as environmental impacts (GHG emissions, land-, nitrogen-, phosphorus-use).
