This report examines how modern electricity grids are experiencing declining levels of inertia as renewable energy and decentralized power generation expand. It explores the implications for grid reliability, the operational challenges facing system operators, and the strategies emerging to maintain stable and resilient electricity systems.

The MESIA Solar Outlook Report analyzes the rapid expansion of solar energy across the Middle East and North Africa (MENA), highlighting installed capacity growth, investment flows, policy frameworks, and emerging market opportunities. The report evaluates how large-scale solar deployment, regulatory reforms, and energy diversification strategies are shaping the region’s renewable energy transition.

The EU’s biomethane market has been developing at speed. Since 2023, production has risen more than 30% and the fuel is fast becoming not just an instrument to reach energy transition targets but is also making a real contribution to security of supply.

The inaugural Editorial of the journal through which we pledged our commitment to improving the lives of half the world's population by acting as their voice and serving as a platform for continued advocacy on their behalf. Much has been written about problems in women's health; now is the time for solutions. Many of the historic issues in women's health will not be resolved overnight. The Lancet Obstetrics, Gynaecology, & Women's Health will continue this legacy and integrate women's health with obstetrics and gynaecology as an indivisible alliance between communities and disciplines.

In this target trial emulation study, prophylactic antibiotic use did not raise the risk of hospital admission due to antibiotic-resistant or urinary tract infections, however it did increase the risk of antibiotic resistance in uropathogens and multidrug resistance detected in urine cultures. This study offers new data on the absolute risk and number needed to harm for individual antibiotic resistance, which can inform shared decision-making discussions on preventing recurrent urinary tract infections (rUTIs).

This systematic review and meta-analysis of 81 included studies synthesised available data on the prevalence of postpartum haemorrhage and severe postpartum haemorrhage according to objective and subjective blood loss assessment methods and mode of birth (vaginal and caesarean). Authors report that the pooled rates of postpartum haemorrhage and severe postpartum haemorrhage were substantially higher when objective methods of blood loss assessment were used instead of subjective methods.

Probably the first study to establish reference ranges for transient elastography in the third trimester of pregnancy, demonstrating that similar cutoffs can be used to define liver steatosis in this period. By analysing more than 5000 women, we identified maternal and gestational risk factors for steatosis and increased liver stiffness in pregnancy, which include obesity, pre-gestational diabetes, and pre-eclampsia

This study represents the first clinical trial of dichloroacetate, a non-hormonal treatment, for endometriosis-associated pain in 30 women, demonstrating that recruitment and treatment are feasible despite common but manageable side effects. The research directly relates to International Women's Day by addressing endometriosis, a chronic condition affecting an estimated 190 million women worldwide that causes debilitating pelvic pain and infertility, highlighting the urgent need for better treatment options for women's health.

This is the largest cohort study to date of women with hyperemesis gravidarum, and it is the first to explore a wide array of neuropsychiatric and mental health outcomes, including psychotic disorder. Evidence study suggests that while hyperemesis gravidarum increases the risk of poor mental health compared to unaffected pregnancies, the link between its severity and psychiatric burden is complex. The lower depression risk in cases with metabolic disturbance versus mild disease may reflect varying levels of healthcare support.

Findings from this SRMA provide clinical evidence against a clinically significant increase in the risk of autism spectrum disorder, ADHD, or intellectual disability among children born to pregnant individuals who use paracetamol as directed, thereby supporting existing safety recommendations.