This study investigated VGLUT1 and VGLUT2 expression in the medial temporal lobe and superior temporal gyrus in Alzheimer's disease (AD). The findings reveal region-specific vulnerabilities, with significantly lower VGLUT1 in the dentate gyrus and VGLUT2 in the subiculum and superior temporal gyrus, suggesting potential therapeutic targets that require further exploration.
This review describes recent clinical contributors to ginseng components in clinical tests and introduces emerging evidence that ginseng components could be novel candidates for cognitive improvement in older individuals, as ginseng components improve SMI cognition and exhibits add-on effects when co-administered with early AD dementia drugs. The mechanism behind the beneficial effects of ginseng components and how it improves cognition are presented.
This article discusses age-related changes in species-typical behaviors, such as exploration and grooming, in female 5xFAD mouse model of Alzheimer's disease, suggesting that these behaviors may serve as valuable indicators for modeling the decline in activities of daily living observed in AD patients and assessing the efficacy of potential therapeutics.
In this episode of the "World We Want" podcast, Márcia Balisciano interviews Dr. Ana Maria Porras, Assistant Prof of Biomedical Engineering, Crochet Artist, and Science Communicator. They discuss how biomedical engineering is helping develop better treatment strategies for tropical disorders, which have historically received very little attention.
Geographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm!
American Journal of Transplantation, Volume 24, May 2024
Nearly 2.4% of global deaths in 2019 were attributed to cirrhosis, which has increased since 2017. Liver transplantation (LT) is accepted as a lifesaving therapy for patients with complications of cirrhosis or hepatocellular cancer, but there are several barriers toward equitable access. This article outlines ways to reduce the disparities
Interesting study on examining the potential molecular mechanism of YGJ using network pharmacology to investigate how Traditional Chinese Medicine disease treatment offers numerous benefits when treating chronic hepatitis.
This article supports SDG 3 by developing noninvasive tools for predicting liver fibrosis in autoimmune hepatitis patients.
Elsevier,
Bioremediation of Emerging Contaminants from Soils, Soil Health Conservation for Improved Ecology and Food Security, 2024, Pages 465-488
This content aligns with Goals 2, 13, and 15 by highlighting how indigenous soil reclamation practices can enhance agricultural productivity and food security; explaining how healthy soils play a crucial role in climate change adaptation and mitigation through practices like agroforestry; and emphasizing the importance of biodiversity conservation and sustainable land management practices inherent in indigenous knowledge systems,
The study finds that compact urban landscapes increase heat health risks, while green spaces and vegetation can mitigate these risks, highlighting the importance of urban planning for climate adaptation.
The study assesses how different mountain regions worldwide are variably exposed to climate, land use, and human population changes. It highlighting Africa's tropical mountains as most vulnerable and European and North American mountains as potential refugia, informing targeted conservation strategies.
