Articles

AI-based tool for early detection of Alzheimer's disease

Elsevier,

Heliyon, Volume 10, 30 April 2024

The study emphasizes practical application with a user-friendly website, empowering radiologists to predict class probabilities, track disease progression, and visualize patient images in both 2D and 3D formats, contributing significantly to the advancement of early AD detection.
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SDG:

Goal 3: Good health and well-being

Tags:

Health and wellbeing, Global

Potential links between platelets and amyloid-β in the pathogenesis of Alzheimer's disease: Evidence from in vitro, in vivo, and clinical studies

Elsevier,

Experimental Neurology, Volume 374, April 2024

This review explores the role of platelet dysfunction in the pathogenesis of Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA), discussing in vitro, in vivo, and clinical evidence related to platelet activation, adhesion, and aggregation, and highlighting potential therapeutic targets to address amyloid-related AD pathogenesis.
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SDG:

Goal 3: Good health and well-being

Tags:

Health and wellbeing, Global

Electroacupuncture Enhances the Functional Connectivity of Limbic System to Neocortex in the 5xFAD Mouse Model of Alzheimer's Disease

Elsevier,

Neuroscience, Volume 544, 19 April 2024

This study demonstrates that electroacupuncture (EA) improves learning and memory in the 5xFAD mouse model of Alzheimer's disease, likely by enhancing functional connectivity between the hippocampus and neocortex and reducing amyloid-β protein expression and deposition. These findings suggest that EA may positively impact resting-state brain activity and connectivity, contributing to cognitive and motor function improvements in AD.
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SDG:

Goal 3: Good health and well-being
Global

Clinical and cortical trajectories in non-fluent primary progressive aphasia and Alzheimer's disease: A role for emotion processing

Elsevier,

Brain Research, Volume 1829, 15 April 2024

Despite diagnostic challenges in differentiating lvPPA and nfvPPA, particularly in advanced cases, this study reveals divergent clinical courses and highlights the importance of assessing emotion processing capacity in dementia diagnosis and monitoring. Utilizing spatiotemporal LME modelling, the research provides valuable insights into the dynamic changes in brain atrophy and behavior, underscoring the need for ongoing evaluation of clinical requirements for patients and families over the disease course.
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SDG:

Goal 3: Good health and well-being
Global

Cholecystokinin (CCK): a neuromodulator with therapeutic potential in Alzheimer's and Parkinson's disease

Elsevier,

Frontiers in Neuroendocrinology, Volume 73, April 2024

This review discusses the multifaceted physiological functions of cholecystokinin (CCK), its potential neuroprotective effects in Alzheimer’s and Parkinson’s diseases, and its therapeutic implications, including its impact on memory, neurotransmitters, and neuroprotection mechanisms.
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SDG:

Goal 3: Good health and well-being
Global

Mitophagy activation by rapamycin enhances mitochondrial function and cognition in 5×FAD mice

Elsevier,

Behavioural Brain Research, Volume 463, 12 April 2024

This article discusses the potential therapeutic strategy of enhancing mitophagy through rapamycin treatment to alleviate cognitive impairment in Alzheimer's disease by improving mitochondrial dysfunction and neuronal loss, suggesting a novel mechanism for the neuroprotective effects of rapamycin in AD.
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SDG:

Goal 3: Good health and well-being

Tags:

Health and wellbeing, Global

Visual arts talent among adolescents with intellectual disability: The global domain approach

Elsevier,

Thinking Skills and Creativity, 2024, 101523

This study explored talent in adolescents with intellectual disability (ID) by comparing those with and without drawing ability, examining both specific artistic skills and broader cognitive abilities. Results showed that adolescents with ID who have drawing talent also demonstrated higher fluid intelligence, cognitive flexibility, and creative thinking, with participation in art classes further enhancing their artistic performance. The findings support a global view of talent and suggest that giftedness models, such as Renzulli�s three-ring model, may be relevant for individuals with ID.

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SDG:

Goal 4: Quality education

Tags:

Education, Middle East

Serotonergic dysfunction may mediate the relationship between alcohol consumption and Alzheimer’s disease

Elsevier,

Pharmacological Research, Volume 203, May 2024, 107171

The article discusses the potential relationship between alcohol consumptiond the development of Alzheimer's disease (AD), highlighting the role of the serotonergic system as a potential mediator. It synthesizes data from preclinical, clinical, and epidemiological studies to explore how alcohol-induced changes in serotonin function, neuroinflammation, and proteostasis may contribute to the onset and progression of AD

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SDG:

Goal 3: Good health and well-being

Tags:

Health and wellbeing; Health and population, Global

The efficacy of antiviral treatment in chronic hepatitis B patients with hepatic steatosis

Elsevier,

Heliyon, Volume 10, April 2024, e28653

This study investigated antiviral effects in a real-world cohort of non-cirrhotic CHB patients with varying degrees of HS, assessed by transient elastography (TE) with controlled attenuation parameter (CAP).
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SDG:

Goal 3: Good health and well-being

Tags:

Health and wellbeing; Health and population, Global

Necroptosis in aluminum-induced neural cells and animal models of Alzheimer's disease

Elsevier,

Journal of Trace Elements and Minerals, Volume 8,
2024, 100125,

The present article reviews the role of necroptosis, as a novel cell death pathway, in Aluminium-induced Alzheimer’s disease models in vitro and in vivo.

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SDG:

Goal 3: Good health and well-being
Global

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