Goal 3: Good health and well-being

Global

Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease

Redox Biology, Volume 62, June 2023

SCFA contribute to the glutamate-glutamine shuttle by acting on glutamine synthetase. Long-term SCFA diet alleviates cognitive and spatial memory defeat in APP/PS1 mice. Long-term SCFA diet reduces Aβ deposition and abnormal phosphorylation of tau. SCFA promote astrocyte-neuron metabolic coupling to reduce oxidative damage.

Category:

Tags:

Health and wellbeing, Global

A novel fluorogenic reporter substrate for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCγ2): Application to high-throughput screening for activators to treat Alzheimer's disease

SLAS Discovery, Volume 28, June 2023

In this study, a novel reporter substrate named C8CF3-coumarin was synthesized and then characterized, an assay protocol was developed to identify small molecular activators of PLCγ enzymes, and a proof-of-principle high throughput screen was conducted using PLCγ2 and the LOPAC1280 library. These studies showed that C8CF3-coumarin could indeed monitor PLCγ enzyme activity and identify potential small molecule activators from a screen. The identification of such small molecule PLCγ2 activators would be of great utility to the Alzheimer's disease research community by serving as both chemical probes to study the modulation of PLCγ2 and as potential therapeutic agents.

Category:

Tags:

Health and wellbeing, Global

A cross-sectional survey of climate and COVID-19 crises in young people in Indian slums: context, psychological responses, and agency

Elsevier, The Lancet Regional Health - Southeast Asia, Volume 13, June 2023

Background: COVID-19 and the climate crisis have caused unprecedented disruptions across the world. Climate change has affected the mental health and wellbeing of children and adolescent.

Category:

Tags:

Health and wellbeing; Diversity and inclusion, Asia

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities - Chapter 7: Ensuring access to preferences

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities
Person Centered Applications of Behavior Analysis
2023, Pages 139-163

This content aligns with Goal 3: Good Health and Wellbeing and Goal 10: Reduced Inequalities by providing specific aspects of agency supports and services in accordance with identified preferences of adults with severe disabilities.

Category:

Tags:

Health and wellbeing; Health and population; Diversity and inclusion, Global

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities - Chapter 12: Treating with dignity

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities
Person Centered Applications of Behavior Analysis
2023, Pages 275-293

This content aligns with Goal 3: Good Health and Wellbeing and Goal 10: Reduced Inequalities by stressing the importance of human service staff treating adults with severe disabilities with dignity.

Category:

Tags:

Health and wellbeing; Health and population; Diversity and inclusion, Global

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities - Chapter 1: Overview of promoting desired lifestyles among adults with severe autism and intellectual disabilities

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities
Person Centered Applications of Behavior Analysis
2023, Pages 3-14

This content aligns with Goal 3: Good Health and Wellbeing and Goal 10: Reduced Inequalities by discussing the importance of promoting desired lifestyles among adults with severe autism and intellectual disabilities, and how the operations of many adult service agencies fail to promote individually desired lifestyles.

Category:

Tags:

Health and wellbeing; Health and population; Diversity and inclusion, Global

Promoting Desired Lifestyles Among Adults With Severe Autism and Intellectual Disabilities - Chapter 10: Person-centeredness, behavior analysis, and treating challenging behavior

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities: Person Centered Applications of Behavior Analysis, 2023, Pages 217-243

This content aligns with Goal 3: Good Health by providing readers and application of behavior analysis to treat challenging behavior specifically in a person-centered manner.

Category:

Tags:

Diversity and inclusion; Health and population; Health and wellbeing, Global

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities – Chapter 1: Overview of promoting desired lifestyles among adults with severe autism and intellectual disabilities

Promoting Desired Lifestyles Among Adults with Severe Autism and Intellectual Disabilities: Person Centered Applications of Behavior Analysis, 2023, pp 3-14

This chapter emphasizes the need for person-centered approaches to promote desired lifestyles for adults with severe autism and intellectual disabilities, aligning with SDG 3 (Good Health and Well-being) by supporting mental and social well-being, and SDG 10 (Reduced Inequalities) by addressing systemic gaps in adult service delivery and advocating equitable access to individualized care.

Category:

Tags:

Diversity and inclusion; Health and wellbeing; Neurodiversity; Health and population, Global

No woman left behind: achieving cervical cancer elimination among women living with HIV

The Lancet HIV, Volume 10, June 2023

Cervical cancer is the fourth most common malignancy in women of reproductive age globally and specially among women living with HIV in low-income and middle -income countries. This Position Paper shows specific challenges and uncertainties on the way to cervical cancer elimination for women living with HIV and highlights the scarcity of evidence for the effect of interventions in this population. The piece calls for the expansion of HPV immunization programmes for women

Category: