Health and wellbeing

Health and well-being have a central role in the 17 Sustainable Development Goals (SDGs) endorsed by the United Nations, emphasizing the integral part they play in building a sustainable future. The third SDG explicitly calls for ensuring healthy lives and promoting well-being for all at all ages. This goal encompasses a wide range of health objectives, from reducing maternal and child mortality rates, combatting disease epidemics, to improving mental health and well-being. But beyond SDG 3, health is intrinsically linked with almost all the other goals.

When addressing SDG 1, which aims to end poverty, one cannot neglect the social determinants of health. Economic hardship often translates into poor nutrition, inadequate housing, and limited access to health care, leading to a vicious cycle of poverty and poor health. Similarly, achieving SDG 2, ending hunger, also contributes to better health through adequate nutrition, essential for physical and mental development and the prevention of various diseases.

Conversely, the repercussions of climate change, encapsulated in SDG 13, profoundly impact health. Rising global temperatures can lead to increased spread of infectious diseases, compromised food and water supplies, and increased frequency and intensity of extreme weather events, all posing severe health risks. Conversely, the promotion of good health can also mitigate climate change through the reduction of carbon-intensive lifestyles and adoption of healthier, more sustainable behaviors.

SDG 5, advocating for gender equality, also has substantial health implications. Ensuring women's access to sexual and reproductive health services not only improves their health outcomes, but also contributes to societal and economic development. Furthermore, achieving SDG 4, quality education, is also critical for health promotion. Education fosters health literacy, empowering individuals to make informed health decisions, hence improving overall community health.

Lastly, SDG 17 underlines the importance of partnerships for achieving these goals. Multi-sector collaboration is vital to integrate health considerations into all policies and practices. Stakeholders from various sectors, including health, education, agriculture, finance, and urban planning, need to align their efforts in creating sustainable environments that foster health and well-being.

Hence, the relationship between health, well-being, and the SDGs is reciprocal. Improving health and well-being helps in achieving sustainable development, and vice versa. In this context, health and well-being are not just outcomes but are also powerful enablers of sustainable development. For the world to truly thrive, it must recognize and act upon these interconnections.

This backstory highlights the importance of interdisciplinary and participatory approaches in advancing the One Health concept, using lessons from an international workshop in Lao PDR to address existing knowledge gaps and improve global health security strategies.

Elsevier,

International Journal of Clinical and Health Psychology, Volume 25, 1 April 2025

This study provides evidence of distinct alterations in resting-state functional connectivity in individuals with amnestic mild cognitive impairment (aMCI) and late-life depression (LLD), underscoring region-specific vulnerabilities that may contribute to cognitive decline and depressive symptomatology in older adults.
This study identifies two CSF proteomic panels that accurately stage Alzheimer’s pathology, outperform current biomarkers, and predict dementia progression over 10 years, enhancing diagnosis and clinical trial stratification.
The article describes the discovery and development of compound 8e, a selective and reversible butyrylcholinesterase (BuChE) inhibitor, as a potential therapeutic agent for treating Alzheimer's disease (AD). Compound 8e exhibited favorable blood-brain barrier permeability, good drug-likeness properties, and pronounced neuroprotective efficacy in various AD models, including zebrafish, scopolamine-induced mice, and APP/PS1 transgenic mice.
This study demonstrated that physical exercise pretreatment improves recognition memory and enhances structural synaptic plasticity in the hippocampus of Alzheimer’s disease (AD) rats, primarily through the activation of hippocampal TREM2. Blocking TREM2 diminished these neuroprotective effects, indicating that exercise mitigates synaptic injury and cognitive decline in AD via a TREM2-dependent mechanism.
Elsevier,

Journal of Allergy and Clinical Immunology: In Practice, Volume 13, April 2025

Foods are essential for life, but foods can be life-threatening for people with food allergy. This collection of articles from the April 2025 issue of JACI: In Practice provides up to date information on many important aspects of food allergy
Sustainable healthy diets in South Asia require a deeper understanding of food choice drivers at household, adolescent, and market levels. Addressing knowledge gaps through interdisciplinary research, improved measurement tools, and collaborative efforts is vital for guiding policy and program interventions. As food systems rapidly transform and ultraprocessed foods proliferate, targeted research and evidence-based strategies are essential to promote healthy, equitable, and sustainable diets for all populations in the region.
This study investigates whether food fermentation in space is possible and if so, how it compares with fermentation on Earth.
Elsevier,

Journal of Allergy and Clinical Immunology: In Practice, Volume 13, April 2025

Foods are essential for life, but foods can be life-threatening for people with food allergy. This collection of articles from the April 2025 issue of JACI: In Practice provides up to date information on many important aspects of food allergy
Elsevier,

Journal of Allergy and Clinical Immunology: In Practice, Volume 13, April 2025

Foods are essential for life, but foods can be life-threatening for people with food allergy. This collection of articles from the April 2025 issue of JACI: In Practice provides up to date information on many important aspects of food allergy

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