New foods for sustainable consumption.

A Viewpoint on the interplay between social, climate, and health challenges in Latin America and the Caribbean, in the context of SDGs 3, 10, and 13, highlighting the need to address these challenges with adaption and mitigation policies that prioritise people's health and wellbeing.

An estimated 50 million people around the world currently live with Alzheimer's disease or other dementias, dementia being a collective term for progressive syndromes that affect various expressions of cognitive function, such as memory and emotional expression. Alzheimer’s disease accounts for the majority of cases (50 to 70%, varying by country, based on Alzheimer’s Disease International and World Health Organization figures).

This book chapter advances SDG #3 and #10 by focusing on polyphenols and flavonoids and their crucial role in decreasing AD symptoms. In addition, it highlights the neuroprotective role of various essential ingredients of plant extracts such as Icariside, Onjisaponin B, Asarones, Liquiritin, Tanshinone IIA (TIIA) and cryptotanshinone (CT), Ginsenoside Rg1, and n-Butylidenephthalide. The efficacy of green nanotechnology are also discussed.

This book chapter advances SDG #3 and #10 by reviewing the risk factors for Alzheimer’s Disease, including normal aging, diet, sedentary lifestyle, sleep disturbances, genes [amyloid precursor protein (APP), presenilin 1 (PSEN1), PSEN2, and APOE], environmental factors, and epigenetic factors.

This book chapter advances SDG #3 and #10 by reviewing several key topics that influence our understanding of pathogenic mechanisms and lead to the identification of novel therapeutic strategies. These include the diagnostic spectrum of MCI and AD, genetic risk alleles associated with late-onset AD, structures of gamma-secretase and tau, imaging and fluid biomarkers, the role of microglia and neuroinflammation, and novel animal models of AD.