Health and wellbeing

Health and well-being have a central role in the 17 Sustainable Development Goals (SDGs) endorsed by the United Nations, emphasizing the integral part they play in building a sustainable future. The third SDG explicitly calls for ensuring healthy lives and promoting well-being for all at all ages. This goal encompasses a wide range of health objectives, from reducing maternal and child mortality rates, combatting disease epidemics, to improving mental health and well-being. But beyond SDG 3, health is intrinsically linked with almost all the other goals.

When addressing SDG 1, which aims to end poverty, one cannot neglect the social determinants of health. Economic hardship often translates into poor nutrition, inadequate housing, and limited access to health care, leading to a vicious cycle of poverty and poor health. Similarly, achieving SDG 2, ending hunger, also contributes to better health through adequate nutrition, essential for physical and mental development and the prevention of various diseases.

Conversely, the repercussions of climate change, encapsulated in SDG 13, profoundly impact health. Rising global temperatures can lead to increased spread of infectious diseases, compromised food and water supplies, and increased frequency and intensity of extreme weather events, all posing severe health risks. Conversely, the promotion of good health can also mitigate climate change through the reduction of carbon-intensive lifestyles and adoption of healthier, more sustainable behaviors.

SDG 5, advocating for gender equality, also has substantial health implications. Ensuring women's access to sexual and reproductive health services not only improves their health outcomes, but also contributes to societal and economic development. Furthermore, achieving SDG 4, quality education, is also critical for health promotion. Education fosters health literacy, empowering individuals to make informed health decisions, hence improving overall community health.

Lastly, SDG 17 underlines the importance of partnerships for achieving these goals. Multi-sector collaboration is vital to integrate health considerations into all policies and practices. Stakeholders from various sectors, including health, education, agriculture, finance, and urban planning, need to align their efforts in creating sustainable environments that foster health and well-being.

Hence, the relationship between health, well-being, and the SDGs is reciprocal. Improving health and well-being helps in achieving sustainable development, and vice versa. In this context, health and well-being are not just outcomes but are also powerful enablers of sustainable development. For the world to truly thrive, it must recognize and act upon these interconnections.

The New Public Health (Fourth Edition), 2023, Pages 1097-1158

This chapter advances the UN SDG Goal 3: Good Health and Goal 10: Reduced Inequalities. It examines the globalization of health as there is increase focus on the international transfer of diseases and the imperative of cooperating to combat inequity under societal conditions that create the spread of diseases and their effects on individual nations and the global community.
This Article supports SDG 3 by analysing several cohorts of people with HIV/HCV co-infection across 6 high-income countries, and identifying that a substantial proportion had not commenced direct-acting antiviral treatment for HCV infection despite unrestricted access. Factors associated with commencement or lack thereof are explored; for example, people with indicators of low engagement with HIV care (eg, not on antiretroviral therapy) were more likely not to have commenced HCV direct-acting antiviral treatment)
This Article supports SDG 3 by providing the first comprehensive review of the global burden of hepatis B and C in people with tuberculosis, through a systematic review and meta-analysis including 127 studies. The review found a high prevalence of these infections in this patient population, showing the need for routine hepatitis testing at the point of diagnosis of tuberculosis.
This review will spur more investigations on microplastic ingestion in historical specimens to establish reference points and determine temporal trends for microplastic pollution of the environment.
This study was designed to explore the relationship between Alzheimer's disease (AD) rates and socioeconomic conditions in 120 countries. We used mixed effect models to investigate the relationship between the rates of AD and socioeconomic data. This study is among the first studies to put forward statistical evidence of a significant association between AD and other dementias among the elderly and socioeconomic inequality. These findings could help to inform the policies to be designed to improve the quality of interventions for AD.
This paper applies stochastic process models (SPM) to study Alzheimer's disease (AD) using data on AD onset and longitudinal body mass index (BMI) trajectories, revealing that APOE e4 carriers are less resilient to deviations in BMI, with age-related declines in adaptive response and differences in allostatic load accumulation, thereby providing new insights into the connections between age, genetic factors, and risk factors in AD development and aging.
This review discusses the link between isolation, loneliness, and Alzheimer's Disease, and underscores the necessity of understanding and addressing these risk factors to develop successful prevention and treatment approaches.
Growing evidence suggests that the gut microbiome plays a crucial role in Alzheimer's disease (AD) pathogenesis through the microbiota-gut-brain axis, with alterations in gut microbiome composition linked to increased intestinal permeability, blood-brain barrier impairment, and neuroinflammation, and that gut microbiome modulation may alleviate AD symptoms, serve as a preventive measure, and also address comorbidities like Type 2 Diabetes Mellitus (T2DM), with future research directions including fecal microbiota transplantation (FMT) and precision medicine.
This article investigates the potential therapeutic effects of glutamic-oxaloacetic transaminase (GOT) in Alzheimer's disease (AD) by reducing glutamate concentrations in the hippocampi of mice, leading to improved neurological function, reduced β-amyloid protein levels, enhanced cognitive performance, increased neuron count and synaptic density, and altered protein expression, suggesting a promising treatment approach for early-stage AD.
This study is a long-term monitoring study in which inter-seasonal relations are established. Thus, the spread of MP pollution in the region during the year was provided by an important bio-indicator.

Pages