Health and wellbeing

Health and well-being have a central role in the 17 Sustainable Development Goals (SDGs) endorsed by the United Nations, emphasizing the integral part they play in building a sustainable future. The third SDG explicitly calls for ensuring healthy lives and promoting well-being for all at all ages. This goal encompasses a wide range of health objectives, from reducing maternal and child mortality rates, combatting disease epidemics, to improving mental health and well-being. But beyond SDG 3, health is intrinsically linked with almost all the other goals.

When addressing SDG 1, which aims to end poverty, one cannot neglect the social determinants of health. Economic hardship often translates into poor nutrition, inadequate housing, and limited access to health care, leading to a vicious cycle of poverty and poor health. Similarly, achieving SDG 2, ending hunger, also contributes to better health through adequate nutrition, essential for physical and mental development and the prevention of various diseases.

Conversely, the repercussions of climate change, encapsulated in SDG 13, profoundly impact health. Rising global temperatures can lead to increased spread of infectious diseases, compromised food and water supplies, and increased frequency and intensity of extreme weather events, all posing severe health risks. Conversely, the promotion of good health can also mitigate climate change through the reduction of carbon-intensive lifestyles and adoption of healthier, more sustainable behaviors.

SDG 5, advocating for gender equality, also has substantial health implications. Ensuring women's access to sexual and reproductive health services not only improves their health outcomes, but also contributes to societal and economic development. Furthermore, achieving SDG 4, quality education, is also critical for health promotion. Education fosters health literacy, empowering individuals to make informed health decisions, hence improving overall community health.

Lastly, SDG 17 underlines the importance of partnerships for achieving these goals. Multi-sector collaboration is vital to integrate health considerations into all policies and practices. Stakeholders from various sectors, including health, education, agriculture, finance, and urban planning, need to align their efforts in creating sustainable environments that foster health and well-being.

Hence, the relationship between health, well-being, and the SDGs is reciprocal. Improving health and well-being helps in achieving sustainable development, and vice versa. In this context, health and well-being are not just outcomes but are also powerful enablers of sustainable development. For the world to truly thrive, it must recognize and act upon these interconnections.

In the context of applying machine learning to solve problems for risk prediction, disease detection, and treatment evaluation, EHR pose many challenges– they do not have a consistent, standardized format across institutions particularly in US, can contain human errors and introduce collection biases. In addition, some institutions or geographic regions do not have access to the technology or financial resources necessary to implement EHR, thus resulting in vulnerable and disadvantaged communities not being electronically visible.
International Day for the Elimination of Racial Discrimination, 21 March 2023
The International Day for the Elimination of Racial Discrimination is observed annually on the day the police in Sharpeville, South Africa, opened fire and killed 69 people at a peaceful demonstration against apartheid "pass laws" in 1960. The UN General assembly created this day to signify the struggle to end the policy of apartheid in South Africa and call on the the international community to end all forms of racial discrimination.
WGS data revealed that herpesvirus/anelloviruses are naturally found in European populations. This represents the first comprehensive research on the plasma virome of pregnant Turkish women.
This Article supports SDG 3 by providing the first systematic review on uptake of testing and treatment and turnaround times to treatment initiation with point-of-care HCV testing versus standard laboratory testing, finding improvements on both fronts; this is reflected in new WHO recommendations on adoption of point-of-care HCV testing as an alternative to laboratory-based tests.
This article aligns with the SDG goal 3 of Good health by showing that hepatitis E superinfection accelerate disease progression and increase long-term mortality in patients with hepatitis B liver cirrhosis
Elsevier,

The Lancet Psychiatry, Volume 10, Issue 4, April 2023, Pages 240-242

People who attempt suicide should be offered help, not punishment, supporting SDG 3, 10, 17.
Elsevier,

One Earth, Volume 5, Issue 2, 2022, Pages 140-141

Gilbert Houngbo is the chair of UN-Water and president of International Fund for Agricultural Development. In this Q&A, he discusses global progress and remaining challenges to achieving clean water for all.
Elsevier,

Advances in Immunology
Volume 157, 2023, Pages 59-100

This content aligns with Goal 3: Good Health and Wellbeing by summarize the current understanding of inflammasome biology and the role of different inflammasomes in HIV pathogenesis with a focus on the recently described CARD8 inflammasome.
The paper proposes that Alzheimer's disease may be the consequence of a maladaptation to an evolutionary-based survival pathway triggered by fructose metabolism, which initially helps preserve critical brain functioning during starvation but becomes injurious when engaged for extensive periods. Although more studies are needed on the role of fructose metabolism and its metabolite, uric acid, in Alzheimer’s disease, it is suggested that both dietary and pharmacologic trials to reduce fructose exposure or block fructose metabolism should be performed to determine whether there is potential benefit in the prevention, management, or treatment of this disease.
Our results suggested that the therapeutic effects of NFP on AD were associated with synaptic- and mitochondrial-related pathways, and they provided targets for further rigorous studies on precise understanding of the molecular mechanism of NFP.

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