This content aligns with Goal 3: Good Health and Wellbeing as well as Goal 10: Reduced Inequalities by emphasizing the importance of technology assessment capability in shaping health policy and priorities to improve health outcomes and quality of life. By promoting strong professional education and practice standards, accreditation processes, and educational programs for public health, the content supports efforts to enhance the quality of healthcare services and public health interventions. Additionally, it aligns with Goal 10: Reduced Inequalities by recognizing the need to address disparities and ensure equitable access to evidence-based methods of prevention, diagnosis, and therapy. By advocating for continuous revision of legal frameworks and ethical standards in response to societal changes and emerging health challenges, the content underscores the importance of promoting fairness and equity in public health practices and policies. Moreover, it highlights the ethical imperative of public health interventions to protect populations from illness and premature death, thereby contributing to efforts aimed at reducing inequalities in health outcomes and promoting the well-being of all members of society.
Elsevier,
Genomic Data Sharing, Case Studies, Challenges, and Opportunities for Precision Medicine, 2023, Pages 71-90
The Global Alliance for Genomics and Health (GA4GH) is an international standards development organization (SDO) focused on advancing human health and medicine through genomic data sharing and interoperability. Founded in 2013, the organization has evolved over time and has adapted to unexpected challenges in ways that we believe would be of interest to the broad biomedical community. In this chapter, we present our experiences to support others wishing to share data through global, community-driven standards supporting SDG3.
The growth of predictive data analytics and the simultaneous growth in the availability of interoperable AI-enabled devices offer opportunities to mitigate healthcare disparities currently endemic in indigent, underrepresented, and underserved communities supporting SDG3.
Elsevier,
Genomic Data Sharing, Case Studies, Challenges, and Opportunities for Precision Medicine, 2023, Pages 71-90
The Global Alliance for Genomics and Health (GA4GH) is an international standards development organization focused on advancing human health and medicine through genomic data sharing and interoperability. Founded in 2013, the organization has evolved over time and has adapted to unexpected challenges. Three themes have emerged as critical to the organization's success: (1) community needs must drive development; (2) agility is necessary to create global equity and opportunity; (3) developing an idea into a widely adopted standard requires multiple levels of consensus furthering SDG3.
With the aging global population, the relationship between older people and their residential environments is increasingly important. This relationship is based on the match between the individual characteristics of a person, their needs and expectations, and the characteristics of their environment. By creating access to various health improvement factors and exposure to various risk factors, the conditions under which an individual ages can be modified. This helps to accelerate or decelerate the process of incapacitation that individuals undergo as they age. This can also reduce or reinforce socio-spatial inequalities, which underlie the preponderant role of territory and spatial policies in the prevention and promotion of healthy aging. This chapters supports the process for developing the Decade of Healthy Ageing (2020 – 2030) aligned to the Sustainable Development Goals (SDG3).
An estimated 50 million people around the world currently live with Alzheimer's disease or other dementias, dementia being a collective term for progressive syndromes that affect various expressions of cognitive function, such as memory and emotional expression. Alzheimer’s disease accounts for the majority of cases (50 to 70%, varying by country, based on Alzheimer’s Disease International and World Health Organization figures).
Diagnosis and Treatment of Traumatic Brain Injury, 2022, Pages 27-38
This book chapter advances SDG #3 and #10 by focusing on an emblematic delayed-onset pathology often seen after traumatic brain injury—Alzheimer’s disease—and explain its relationship with chronic traumatic encephalopathy.
Plant Extracts in Neurodegenerative Diseases, 2022, Pages 1-15
This book chapter advances SDG #3 and #10 by focusing on polyphenols and flavonoids and their crucial role in decreasing AD symptoms. In addition, it highlights the neuroprotective role of various essential ingredients of plant extracts such as Icariside, Onjisaponin B, Asarones, Liquiritin, Tanshinone IIA (TIIA) and cryptotanshinone (CT), Ginsenoside Rg1, and n-Butylidenephthalide. The efficacy of green nanotechnology are also discussed.
Exercise to Prevent and Manage Chronic Disease Across the Lifespan, 2022, Pages 413-421
This book chapter advances SDG #3 and #10 by outlining the pathophysiology associated with Alzheimer’s disease and provide an overview of the impact of exercise programs on cognition, physical functional abilities, behavioral, and psychological symptoms and quality of life.
Neurobiology of Brain Disorders (Second Edition), Biological Basis of Neurological and Psychiatric Disorders, 2022, Pages 313-336
This book chapter advances SDG #3 and #10 by reviewing several key topics that influence our understanding of pathogenic mechanisms and lead to the identification of novel therapeutic strategies. These include the diagnostic spectrum of MCI and AD, genetic risk alleles associated with late-onset AD, structures of gamma-secretase and tau, imaging and fluid biomarkers, the role of microglia and neuroinflammation, and novel animal models of AD.
