This book chapter advances SDG #3 and #10 by reviewing the extant literature on autophagy in AD and covers recent progress on the molecular mechanisms of NAD+-dependent mitophagy/autophagy regulation and mechanisms underlying the anti-AD potential of NAD+. Further studies to define the NAD+-mitophagy/autophagy axis may shed light on novel therapeutics to treat AD and potentially provide insights into other neurodegenerative diseases.
Elsevier,
Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging, Volume , 1 January 2021
This book chapter advances SDG #3 and #10 by reviewing the use of nonhuman primates as a viable model of aging and neurodegeneration research.
This book chapter advances SDG #3 and #10 by reviewing deep brain stimulation as a treatment for AD patients, reviewing the recent studies and issues associated with the treatment.
This book chapter advances SDG #3 and #10 by reviewing the observed epidemiological links between normal and abnormal diurnal and seasonal rhythmicity, cognitive impairment, and ADRD. Then reviewing normal diurnal and seasonal rhythms of brain epigenetic modification and gene expression in model organisms. Finally, reviewing evidence for diurnal and seasonal rhythms of epigenetic modification and gene expression the human brain in aging, Alzheimer's disease, and other brain disorders.
Critical knowledge gaps about environmental fate and unintentional effects of currently used pesticides (CUPs) hamper the understanding and mitigation of their global impacts on ecological processes. We investigated the exposure of earthworms to 31 multiclass CUPs in an arable landscape in France. We highlighted the presence of at least one pesticide in all soils (n = 180) and 92 % of earthworms (n = 155) both in treated crops and nontreated habitats (hedgerows, grasslands, and cereals under organic farming).
Purpose: Besides diagnostic imaging devices, in particular computed tomography (CT) and magnetic resonance imaging (MRI), numerous reading workstations contribute to the high energy consumption of radiological departments. It was investigated whether switching off workstations after core working hours can relevantly lower energy consumption considering both ecological and economical aspects.
The consumption of meat contributes significantly to undesirable effects on the environment. In order to reduce the impact of animal husbandry, one approach is to decrease meat consumption by substituting plant-based meat alternatives. Because the consumption of such meat alternatives is currently rather low, the aim of this research was to identify the barriers that keep people from consuming meat alternatives and increase the probability of future consumption.
Background: Today's meat and dairy industry has a vast environmental footprint. To reach the UN sustainable development goals (SDGs) of ending hunger globally (SDG #2) and achieving sustainable consumption and production (SDG #12), this food production system needs to change. Recent years have seen the rise in popularity of the vegan or plant-based diet among consumers, which can go some way to reducing the environmental burden.
Perceived discrimination, intergroup contact and acceptance are often encountered during acculturation processes. Based on large-scale survey data collected in the Netherlands among Antillean-Dutch, Moroccan-Dutch, Surinamese-Dutch, and Turkish-Dutch immigrant groups, relations were tested between acculturation antecedents (perceived discrimination, intergroup contact, and perceived acceptance), mediating conditions (cultural maintenance and cultural adoption), and acculturation outcomes (psychological and sociocultural outcomes).
In limestone quarries, after quarry abandonment, ecological restoration takes place subsequently over several years, often with the use of different procedures and backfilling materials. The success of the different restoration actions performed at a limestone quarry (Colle Pedrino, Lombardy Prealps, Italy) in terms of vegetation cover and biodiversity levels, compared to the surrounding natural areas, was evaluated in this work.
