This article investigates the distribution and levels of tau and other neuronal proteins in the submandibular gland and frontal cortex of individuals at different clinicopathological stages of Alzheimer's disease (AD), revealing differential protein levels and the presence of unique tau species in peripheral tissues, providing insights into the relationship between peripheral tissues and AD progression.
This article reviews collaborative mindset required to tackle global problem of AD.
Introduction and Objectives: We initiated this multicenter study to integrate important risk factors to create a nomogram for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) for clinician decision-making. Patients and Methods: Between April 2011 and March 2022, 2281 HCC patients with an HBV-related diagnosis were included. All patients were randomly divided into two groups in a ratio of 7:3 (training cohort, n = 1597; validation cohort, n = 684). The nomogram was built in the training cohort via Cox regression model and validated in the validation cohort.
This Review supports SDGs 3 and 13 by summarising the available literature on the impacts of climate change on airborne allergens and allergic respiratory diseases, with a focus on recent developments. The authors also focus on three translational mitigation approaches that may lead to improved health outcomes: automated real-time airborne allergen monitoring, airborne allergen forecasting and modelling, and smartphone apps for mitigating the health impacts of airborne allergens.
This Review supports SDGs 3 and 13 by synthesizing the recent evidence on whether and how climate change, manifested in meteorological fluctuations, extreme weather events, and long-term global warming, influences the epidemic dynamics of viral respiratory infections, including spatiotemporal distribution of seasonal epidemic, disease outbreaks, and pandemics.
Female sex workers are a key population for HIV control. This study uses data from Zimbabwe's national sex worker programme to shed light on HIV outcomes in this important population.
Tuberculosis is a major contributor of morbidity and mortality in people living with HIV. This study investigates treatment of coinfection with the current first-line treatments for both infections.
This article supports SDG 3 by evaluating the outcomes of early liver transplantation for alcohol-associated hepatitis.
This paper looks at the role of the circadian clock and the regulation of HIV-1 replication.
This paper evaluates new indications and key mechanism of a clinically approved drug Bazi Bushen capsule for treatment of Aizheimer's disease using network pharmacology approach.
