This book chapter advances SDG 3 and 10 by describing and discussing (1) the existing evidence examining associations between mental health and technology use including depression, anxiety, body dissatisfaction, attention-deficit disorders (and risks of distraction), and addictive behaviors and (2) the impacts of risky online communities on adolescents’ mental health, focusing on networks promoting proeating disorder behaviors and prosuicidality.
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive decline in cognitive function. Intracerebroventricular injection of streptozotocin (icv-STZ) has been used as an experimental model of Sporadic AD (SAD) in rodents and represents a promising tool for etiopathogenic analysis and evaluation of new therapeutic proposals for AD. The icv-STZ model shows many aspects of SAD abnormalities, resulting in decreased brain glucose and energy metabolism, cognitive impairment, oxidative stress, neuronal loss, and amyloid angiopathy.
Elsevier,
Diagnosis and Management in Dementia: The Neuroscience of Dementia, Volume 1, Volume , 1 January 2020
This book chapter advances SDG #3 and #10 by outlining how both the asymptomatic and symptomatic predementia phases of AD, amyloid positivity using amyloid PET imaging could predict progression to AD dementia. Amyloid PET imaging can identify the status of Aβ deposition in the underlying AD pathophysiology, increase diagnostic certainty, and alter management. This approach could improve the diagnose and management for patients with memory loss or cognitive dysfunction.
Elsevier,
Diagnosis and Management in Dementia: The Neuroscience of Dementia, Volume 1, Volume , 1 January 2020
This book chapter advances SDG #3 and #10 by focusing on providing a brief overview of genes associated with sporadic (late-onset) Alzheimer's disease (AD).
This book chapter advances SDG #3 and #10 by reviewing background on neurocognitive disorders, approaches to diagnosis, and management of several of the more problematic psychiatric complications of dementia. Disorders reviewed include AD, vascular dementia, Lewy body disease, and frontotemporal dementia. Psychiatric symptoms reviewed include apathy, agitation, psychosis, depression, and anxiety.
Elsevier,
Diagnosis and Management in Dementia: The Neuroscience of Dementia, Volume 1, Volume , 1 January 2020
This book chapter advances SDG #3 and #10 by providing an overview of natural AChE inhibitors extracted from plants and their therapeutic potential to treat AD.
This book chapter advances SDG 3 and 10 by providing best practices and applied examples to instruct human factors practitioners (researchers and designers) in creating health-care designs that are inclusive of various populations.
This book chapter advances SDG 3 and 10 by exploring the current state of design as applied to global health, models of how it is carried out, and some of the questions that arise for practitioners. The goal of this chapter is to help practioners design models to help improve health and well-being of people in lower income countries.
A new threat now confronts the Amazon in the form of a massive infrastructure program, the Initiative for the Integration of the Regional Infrastructure of South America, or IIRSA. This article presents results of a projection analysis showing that IIRSA could push the Amazonian forest past a “tipping point,” replacing it with tropical savanna. Such an event would degrade biodiversity, reduce carbon storage, and harm continental agriculture, dependent on moisture transport from forest-based rainfall recycling.
Purpose: Although the wind, rain, and flooding of Hurricane Maria in Puerto Rico abated shortly after its landfall on September 20, 2017, the disruption of the electrical, communications, transportation, and medical infrastructure of the island was unprecedented in scope and caused lasting harm for many months afterward. A compilation of recommendations from radiation oncologists who were in Puerto Rico during the disaster, and from a panel of American Society for Radiation Oncology (ASTRO) cancer experts was created.
